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  1. The CRISPR/Cas9 is currently the predominant technology to enhance the genome editing efficiency in eukaryotes. Established tools for many fungal species exist while most of them are based on in vivo expressed...

    Authors: Joosu Kuivanen, Veera Korja, Sami Holmström and Peter Richard

    Citation: Fungal Biology and Biotechnology 2019 6:3

    Content type: Research

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  2. The bacterial CRISPR/Cas genome editing system has provided a major breakthrough in molecular biology. One use of this technology is within a nuclease-based gene drive. This type of system can install a geneti...

    Authors: Megan E. Goeckel, Erianna M. Basgall, Isabel C. Lewis, Samantha C. Goetting, Yao Yan, Megan Halloran and Gregory C. Finnigan

    Citation: Fungal Biology and Biotechnology 2019 6:2

    Content type: Short Report

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  3. Itaconic acid (IA), a C5-dicarboxylic acid, has previously been identified as one of the top twelve biochemicals that can be produced by biotechnological means. IA is naturally produced by Aspergillus terreus, ho...

    Authors: Abeer H. Hossain, Alexander Ter Beek and Peter J. Punt

    Citation: Fungal Biology and Biotechnology 2019 6:1

    Content type: Research

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  5. Filamentous fungi are important producers of secondary metabolites, low molecular weight molecules that often have bioactive properties. Calbistrin A is a secondary metabolite with an interesting structure tha...

    Authors: Sietske Grijseels, Carsten Pohl, Jens Christian Nielsen, Zahida Wasil, Yvonne Nygård, Jens Nielsen, Jens C. Frisvad, Kristian Fog Nielsen, Mhairi Workman, Thomas Ostenfeld Larsen, Arnold J. M. Driessen and Rasmus John Normand Frandsen

    Citation: Fungal Biology and Biotechnology 2018 5:18

    Content type: Research

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  6. Translocated chromosomal duplications occur spontaneously in many organisms; segmental duplications of large chromosomal regions are expected to result in phenotypic changes because of gene dosage effects. The...

    Authors: Tadashi Takahashi, Masahiro Ogawa, Atsushi Sato and Yasuji Koyama

    Citation: Fungal Biology and Biotechnology 2018 5:17

    Content type: Research

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  7. Aspergillus niger is an important fungus used in industrial applications for enzyme and acid production. To enable rational metabolic engineering of the species, available information can be collected and integra...

    Authors: Julian Brandl, Maria Victoria Aguilar-Pontes, Paul Schäpe, Anders Noerregaard, Mikko Arvas, Arthur F. J. Ram, Vera Meyer, Adrian Tsang, Ronald P. de Vries and Mikael R. Andersen

    Citation: Fungal Biology and Biotechnology 2018 5:16

    Content type: Research

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  8. The filamentous fungus Trichoderma reesei (T. reesei) is a natural producer of cellulolytic and xylanolytic enzymes and is therefore industrially used. Many industries require high amounts of enzymes, in particul...

    Authors: Alice Rassinger, Agnieszka Gacek-Matthews, Joseph Strauss, Robert L. Mach and Astrid R. Mach-Aigner

    Citation: Fungal Biology and Biotechnology 2018 5:15

    Content type: Research

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  9. Itaconate is getting growing biotechnological significance, due to its use as a platform compound for the production of bio-based polymers, chemicals, and novel fuels. Currently, Aspergillus terreus is used for i...

    Authors: Elena Geiser, Hamed Hosseinpour Tehrani, Svenja Meyer, Lars M. Blank and Nick Wierckx

    Citation: Fungal Biology and Biotechnology 2018 5:14

    Content type: Research

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  10. CRISPR/Cas9-based genome editing is quickly becoming a powerful tool within the field of fungal genetics. Adaptation of CRISPR/Cas9 systems are allowing for rapid and highly efficient gene targeting within fun...

    Authors: Qusai Al Abdallah, Ana Camila Oliveira Souza, Adela Martin-Vicente, Wenbo Ge and Jarrod R. Fortwendel

    Citation: Fungal Biology and Biotechnology 2018 5:11

    Content type: Short Report

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  11. Cytochrome P450s form an important group of enzymes involved in xenobiotics degradation and metabolism, both primary and secondary. These enzymes are also useful in industry as biotechnological tools for bioco...

    Authors: Sonia Chadha, Sayaji T. Mehetre, Ravindra Bansal, Alan Kuo, Andrea Aerts, Igor V. Grigoriev, Irina S. Druzhinina and Prasun K. Mukherjee

    Citation: Fungal Biology and Biotechnology 2018 5:12

    Content type: Research

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  13. Trichoderma reesei is one of the most frequently used filamentous fungi in industry for production of homologous and heterologous proteins. The ability to use sexual crossing in this fungus was discovered several...

    Authors: Christoph Dattenböck, Doris Tisch, Andre Schuster, Alberto Alonso Monroy, Wolfgang Hinterdobler and Monika Schmoll

    Citation: Fungal Biology and Biotechnology 2018 5:9

    Content type: Research

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  14. Expanding the application of technical enzymes, e.g., in industry and agriculture, commands the acceleration and cost-reduction of bioprocess development. Microplates and shake flasks are massively employed du...

    Authors: Alexander Eck, Matthias Schmidt, Stefanie Hamer, Anna Joelle Ruff, Jan Förster, Ulrich Schwaneberg, Lars M. Blank, Wolfgang Wiechert and Marco Oldiges

    Citation: Fungal Biology and Biotechnology 2018 5:8

    Content type: Research

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  16. Currently around one billion people in the world do not have access to a diet which provides enough protein and energy. However, the production of one of the main sources of protein, animal meat, causes severe...

    Authors: Pedro F. Souza Filho, Ramkumar B. Nair, Dan Andersson, Patrik R. Lennartsson and Mohammad J. Taherzadeh

    Citation: Fungal Biology and Biotechnology 2018 5:5

    Content type: Research

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  17. Following publication of the original article [1], the authors reported that there is a mistake in the legend of Figure 4; the explanation of the symbols has been mixed up. The corrected version of Figure 4 is...

    Authors: Simon Boecker, Stefan Grätz, Dennis Kerwat, Lutz Adam, David Schirmer, Lennart Richter, Tabea Schütze, Daniel Petras, Roderich D. Süssmuth and Vera Meyer

    Citation: Fungal Biology and Biotechnology 2018 5:7

    Content type: Correction

    Published on:

    The original article was published in Fungal Biology and Biotechnology 2018 5:4

  18. Sequencing of fungal species has demonstrated the existence of thousands of putative secondary metabolite gene clusters, the majority of them harboring a unique set of genes thought to participate in productio...

    Authors: Philipp Wiemann, Alexandra A. Soukup, Jacob S. Folz, Pin-Mei Wang, Andreas Noack and Nancy P. Keller

    Citation: Fungal Biology and Biotechnology 2018 5:6

    Content type: Research

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  19. Fungal cyclodepsipeptides (CDPs) are non-ribosomally synthesized peptides produced by a variety of filamentous fungi and are of interest to the pharmaceutical industry due to their anticancer, antimicrobial an...

    Authors: Simon Boecker, Stefan Grätz, Dennis Kerwat, Lutz Adam, David Schirmer, Lennart Richter, Tabea Schütze, Daniel Petras, Roderich D. Süssmuth and Vera Meyer

    Citation: Fungal Biology and Biotechnology 2018 5:4

    Content type: Research

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    The Correction to this article has been published in Fungal Biology and Biotechnology 2018 5:7

  20. Cinnamon (Cinnamomum zeylanicum) bark extract exhibits potent inhibitory activity against Candida albicans but the antifungal mechanisms of this essential oil remain largely unexplored.

    Authors: Zinnat Shahina, Amira M. El-Ganiny, Jessica Minion, Malcolm Whiteway, Taranum Sultana and Tanya E. S. Dahms

    Citation: Fungal Biology and Biotechnology 2018 5:3

    Content type: Research

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  21. U6 promoters have been used for single guide RNA (sgRNA) transcription in the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas9) genome editing system. However, no ....

    Authors: Xiaomei Zheng, Ping Zheng, Jibin Sun, Zhang Kun and Yanhe Ma

    Citation: Fungal Biology and Biotechnology 2018 5:2

    Content type: Short Report

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  22. Sugarcane distillery waste water (SDW) or vinasse is the residual liquid waste generated during sugarcane molasses fermentation and alcohol distillation. Worldwide, this effluent is responsible for serious env...

    Authors: Graziella Chuppa-Tostain, Julien Hoarau, Marie Watson, Laetitia Adelard, Alain Shum Cheong Sing, Yanis Caro, Isabelle Grondin, Isabelle Bourven, Jean-Marie Francois, Elisabeth Girbal-Neuhauser and Thomas Petit

    Citation: Fungal Biology and Biotechnology 2018 5:1

    Content type: Research

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  25. The dicarboximide fungicide iprodione has been used to combat blackleg disease of canola (Brassica napus), caused by the fungus Leptosphaeria maculans. For example, in Australia the fungicide was used in the late...

    Authors: Alexander Idnurm, Andrew S. Urquhart, Dinesh R. Vummadi, Steven Chang, Angela P. Van de Wouw and Francisco J. López-Ruiz

    Citation: Fungal Biology and Biotechnology 2017 4:12

    Content type: Research

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  26. Ustilago maydis is known for its natural potential to produce a broad range of valuable chemicals, such as itaconate, from both industrial carbon waste streams and renewable biomass. P...

    Authors: Thiemo Zambanini, Sandra K. Hartmann, Lisa M. Schmitz, Linda Büttner, Hamed Hosseinpour Tehrani, Elena Geiser, Melanie Beudels, Dominik Venc, Georg Wandrey, Jochen Büchs, Markus Schwarzländer, Lars M. Blank and Nick Wierckx

    Citation: Fungal Biology and Biotechnology 2017 4:11

    Content type: Research

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  27. The industrial applications of cellulases are mostly limited by the costs associated with their production. Optimized production pathways are therefore desirable. Based on their enzyme inducing capacity, cellu...

    Authors: Lara Hassan, Manfred J. Reppke, Nils Thieme, Steffen A. Schweizer, Carsten W. Mueller and J. Philipp Benz

    Citation: Fungal Biology and Biotechnology 2017 4:10

    Content type: Research

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  29. Penicillium species are important producers of bioactive secondary metabolites. However, the immense diversity of the fungal kingdom is only scarcely represented in industrial bioproce...

    Authors: Sietske Grijseels, Jens Christian Nielsen, Jens Nielsen, Thomas Ostenfeld Larsen, Jens Christian Frisvad, Kristian Fog Nielsen, Rasmus John Normand Frandsen and Mhairi Workman

    Citation: Fungal Biology and Biotechnology 2017 4:8

    Content type: Research

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  30. In the primary transcript of nuclear genes, coding sequences—exons—usually alternate with non-coding sequences—introns. In the evolution of spliceosomal intron–exon structure, extant intron positions can be ab...

    Authors: Michel Flipphi, Norbert Ág, Levente Karaffa, Napsugár Kavalecz, Gustavo Cerqueira, Claudio Scazzocchio and Erzsébet Fekete

    Citation: Fungal Biology and Biotechnology 2017 4:7

    Content type: Research

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  31. The implementation of Agrobacterium tumefaciens as a transformation tool revolutionized approaches to discover and understand gene functions in a large number of fungal species. A. tumefaciens mediated transforma...

    Authors: Alexander Idnurm, Andy M. Bailey, Timothy C. Cairns, Candace E. Elliott, Gary D. Foster, Giuseppe Ianiri and Junhyun Jeon

    Citation: Fungal Biology and Biotechnology 2017 4:6

    Content type: Review

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  33. Filamentous fungi, including the ascomycetes Monascus, Fusarium, Penicillium and Neurospora, are being explored as novel sources of natural pigments with biological functionality for food, feed and cosmetic appli...

    Authors: Rebecca Gmoser, Jorge A. Ferreira, Patrik R. Lennartsson and Mohammad J. Taherzadeh

    Citation: Fungal Biology and Biotechnology 2017 4:4

    Content type: Review

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  34. Cereal rust fungi (Puccinia spp.) are among the most economically important plant pathogens. These fungi have a complex life cycle, including five spore stages and two hosts. They infect one grass host on which t...

    Authors: Anna Berlin, Berit Samils and Björn Andersson

    Citation: Fungal Biology and Biotechnology 2017 4:3

    Content type: Short Report

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  35. Biofinished wood is considered to be a decorative and protective material for outdoor constructions, showing advantages compared to traditional treated wood in terms of sustainability and self-repair. Natural ...

    Authors: Elke J. van Nieuwenhuijzen, Jos A. M. P. Houbraken, Peter J. Punt, Guus Roeselers, Olaf C. G. Adan and Robert A. Samson

    Citation: Fungal Biology and Biotechnology 2017 4:2

    Content type: Research

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  36. Flavin-dependent monooxygenases are involved in key biological processes as they catalyze a wide variety of chemo-, regio- and enantioselective oxygenation reactions. Flavoprotein monooxygenases are frequently...

    Authors: Sandrine Pigné, Agata Zykwinska, Etienne Janod, Stéphane Cuenot, Mohammed Kerkoud, Roxane Raulo, Nelly Bataillé-Simoneau, Muriel Marchi, Anthony Kwasiborski, Guillaume N’Guyen, Guillaume Mabilleau, Philippe Simoneau and Thomas Guillemette

    Citation: Fungal Biology and Biotechnology 2017 4:1

    Content type: Research

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  39. The production of reactive oxygen species (ROS) and a balanced redox homeostasis are essential parameters, which control the infection process of the plant pathogen Botrytis cinerea. The necrotrophic fungus is ab...

    Authors: Robert Marschall, Ulrike Siegmund, Joachim Burbank and Paul Tudzynski

    Citation: Fungal Biology and Biotechnology 2016 3:8

    Content type: Research

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  40. Many Trichoderma species are applied as biofungicides and biofertilizers to agricultural soils to enhance crop growth. These filamentous fungi have the ability to reduce plant diseases and promote plant growth an...

    Authors: Samantha Lee, Melanie Yap, Gregory Behringer, Richard Hung and Joan W. Bennett

    Citation: Fungal Biology and Biotechnology 2016 3:7

    Content type: Research

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  41. The EUROFUNG network is a virtual centre of multidisciplinary expertise in the field of fungal biotechnology. The first academic-industry Think Tank was hosted by EUROFUNG to summarise the state of the art and...

    Authors: Vera Meyer, Mikael R. Andersen, Axel A. Brakhage, Gerhard H. Braus, Mark X. Caddick, Timothy C. Cairns, Ronald P. de Vries, Thomas Haarmann, Kim Hansen, Christiane Hertz-Fowler, Sven Krappmann, Uffe H. Mortensen, Miguel A. Peñalva, Arthur F. J. Ram and Ritchie M. Head

    Citation: Fungal Biology and Biotechnology 2016 3:6

    Content type: Commentary

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  44. The considerable capacity of filamentous fungi for the secretion of proteins is the basis for multi-billion dollar industries producing enzymes and proteins with therapeutic value. The stepwise pathway from t...

    Authors: Martin Schalén, Diana Chinyere Anyaogu, Jakob Blæsbjerg Hoof and Mhairi Workman

    Citation: Fungal Biology and Biotechnology 2016 3:3

    Content type: Research

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  45. Claviceps purpurea is a phytopathogenic fungus infecting a broad range of grasses including economically important cereal crop plants. The infection cycle ends with the formation of th...

    Authors: Lisa Neubauer, Julian Dopstadt, Hans-Ulrich Humpf and Paul Tudzynski

    Citation: Fungal Biology and Biotechnology 2016 3:2

    Content type: Research

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  46. Claviceps purpurea is a pathogen that infects most members of Pooideae, a subfamily of Poaceae, and causes ergot, a floral disease in which the ovary is replaced with a sclerotium. Whe...

    Authors: Barbara S. Gilmore, Stephen C. Alderman, Brian J. Knaus, Nahla V. Bassil, Ruth C. Martin, James E. Dombrowski and Jeremiah K. S. Dung

    Citation: Fungal Biology and Biotechnology 2016 3:1

    Content type: Research

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  47. Fungi of the phylum Basidiomycota are well-known to form a broad spectrum of biologically active secondary metabolites, especially low molecular weight compounds such as terpenoids. Hericium erinaceus produces va...

    Authors: T. Shen, G. Morlock and H. Zorn

    Citation: Fungal Biology and Biotechnology 2015 2:8

    Content type: Short Report

    Published on:

  48. The conventional method used to assess growth of the plasmodium of the slime mold Physarum polycephalum in solid culture is to measure the extent of plasmodial expansion from the point of inoculation by using a r...

    Authors: Hanh T. M. Tran, Steven L. Stephenson and Jason A. Tullis

    Citation: Fungal Biology and Biotechnology 2015 2:7

    Content type: Research

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  49. Authors: Zsófia Büttel, Rafael Díaz, Benedict Dirnberger, Michal Flak, Sietske Grijseels, Min Jin Kwon, Jens Christian Froslev Nielsen, Yvonne Nygård, Pradeep Phule, Carsten Pohl, Sylvain Prigent, Milica Randelovic, Tabea Schütze, Danielle Troppens and Annarita Viggiano

    Citation: Fungal Biology and Biotechnology 2015 2:6

    Content type: Commentary

    Published on:

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Fungal Biology and Biotechnology

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