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  1. Research

    Phytochelatin synthase is required for tolerating metal toxicity in a basidiomycete yeast and is a conserved factor involved in metal homeostasis in fungi

    Phytochelatin synthase (PCS) is an enzyme that catalyzes the biosynthesis of phytochelatin from glutathione. Phytochelatins protect cells against the toxic effects of non-essential heavy metals, such as cadmiu...

    Alaina M Shine, Viplendra PS Shakya and Alexander Idnurm

    Fungal Biology and Biotechnology 2015 2:3

    Published on: 28 March 2015

  2. Research

    Penicillium nalgiovense Laxa isolated from Antarctica is a new source of the antifungal metabolite amphotericin B

    The need for new antibiotic drugs increases as pathogenic microorganisms continue to develop resistance against current antibiotics. We obtained samples from Antarctica as part of a search for new antimicrobia...

    K Stefan Svahn, Erja Chryssanthou, Björn Olsen, Lars Bohlin and Ulf Göransson

    Fungal Biology and Biotechnology 2015 2:1

    Published on: 17 January 2015

  3. Short Report

    Next-generation genome sequencing can be used to rapidly characterise sequences flanking T-DNA insertions in random insertional mutants of Leptosphaeria maculans

    Banks of mutants with random insertions of T-DNA from Agrobacterium tumefaciens are often used in forward genetics approaches to identify phenotypes of interest. Upon identification of mutants of interest, the fl...

    Kylie Chambers, Rohan GT Lowe, Barbara J Howlett, Manuel Zander, Jacqueline Batley, Angela P Van de Wouw and Candace E Elliott

    Fungal Biology and Biotechnology 2014 1:10

    Published on: 7 December 2014

  4. Research

    The capacity of Aspergillus niger to sense and respond to cell wall stress requires at least three transcription factors: RlmA, MsnA and CrzA

    Cell wall integrity, vesicle transport and protein secretion are key factors contributing to the vitality and productivity of filamentous fungal cell factories such as Aspergillus niger. In order to pioneer ratio...

    Markus RM Fiedler, Annett Lorenz, Benjamin M Nitsche, Cees AMJJ van den Hondel, Arthur FJ Ram and Vera Meyer

    Fungal Biology and Biotechnology 2014 1:5

    Published on: 1 December 2014

  5. Research

    RNA-sequencing reveals the complexities of the transcriptional response to lignocellulosic biofuel substrates in Aspergillus niger

    Saprobic fungi are the predominant industrial sources of Carbohydrate Active enZymes (CAZymes) used for the saccharification of lignocellulose during the production of second generation biofuels. The productio...

    Steven T Pullan, Paul Daly, Stéphane Delmas, Roger Ibbett, Matthew Kokolski, Almar Neiteler, Jolanda M van Munster, Raymond Wilson, Martin J Blythe, Sanyasi Gaddipati, Gregory A Tucker and David B Archer

    Fungal Biology and Biotechnology 2014 1:3

    Published on: 17 November 2014

  6. Research

    Exploring fungal biodiversity: organic acid production by 66 strains of filamentous fungi

    Filamentous fungi are well known for their ability to degrade lignocellulosic biomass and have a natural ability to convert certain products of biomass degradation, for example glucose, into various organic ac...

    Nadège Liaud, Christian Giniés, David Navarro, Nicolas Fabre, Sylvaine Crapart, Isabelle Herpoël- Gimbert, Anthony Levasseur, Sana Raouche and Jean-Claude Sigoillot

    Fungal Biology and Biotechnology 2014 1:1

    Published on: 1 November 2014

  7. Review

    Fungal biology in the post-genomic era

    In this review I give a personal perspective of how fungal biology has changed since I started my Ph. D. in 1963. At that time we were working in the shadow of the birth of molecular biology as an autonomous a...

    Claudio Scazzocchio

    Fungal Biology and Biotechnology 2014 1:7

    Published on: 14 October 2014

  8. Research

    Engineering of Aspergillus niger for the production of secondary metabolites

    Filamentous fungi can each produce dozens of secondary metabolites which are attractive as therapeutics, drugs, antimicrobials, flavour compounds and other high-value chemicals. Furthermore, they can be used a...

    Lennart Richter, Franziska Wanka, Simon Boecker, Dirk Storm, Tutku Kurt, Özlem Vural, Roderich Süßmuth and Vera Meyer

    Fungal Biology and Biotechnology 2014 1:4

    Published on: 14 October 2014

  9. Research

    Identification of the UDP-glucose-4-epimerase required for galactofuranose biosynthesis and galactose metabolism in A. niger

    Galactofuranose (Galf)-containing glycoconjugates are important to secure the integrity of the cell wall of filamentous fungi. Mutations that prevent the biosynthesis of Galf-containing molecules compromise cell ...

    Joohae Park, Boris Tefsen, Mark Arentshorst, Ellen Lagendijk, Cees AMJJ van den Hondel, Irma van Die and Arthur FJ Ram

    Fungal Biology and Biotechnology 2014 1:6

    Published on: 14 October 2014

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