Fig. 4
From: Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales
Lindolin biosynthesis in L. pennispora and other Kickxellales. A IAA and lindolin biosyntheses build on l-tryptophan via two unstable intermediates (brackets). Predicted enzymes are shown as grey spheres. Biochemically verified enzymes, i.e. the indole-3-acetic acid-CoA ligase LinA and the indole-3-acetyl-CoA:anthranilate N-indole-3-acetyltransferase LinB, are shown in red and blue spheres, respectively. B Structurally related compounds from oat (avenanthramides A–C) and the antiallergic drug tranilast