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Table 2 Selected pharmaceuticals derived from filamentous fungi and their applications. (Modified after [13])

From: Growing a circular economy with fungal biotechnology: a white paper

β-lactamsPenicillins and cephalosporins account for more than 30% of the global antibiotics market
CyclosporinImmunosuppressant that avoids organ rejection in transplant surgery
DrospirenoneSteroid hormone used as a birth control pill and traded as Slynd; in combination with an oestrogen traded under the brand name Yasmin
EchinocandinsCaspofungin, micafungin and anidulafungin used for the treatment of Candida infections
GriseofulvinAntifungal used for the treatment of skin infections
Mycophenolic acidImmunosuppressant that avoids organ rejection in transplant surgery and is traded as CellCept
MyriocinChemical analogue thereof is used to treat multiple sclerosis; approved in 2018 as Gilenya
PsilocybinIndolalkaloid currently being tested in phase II clinical trials for the treatment of major depressive disorders and is considered by the FDA as a breakthrough therapy [16]
StatinsLovastatin, simvastatin and pravastatin are used to treat cardiovascular diseases by lowering cholesterol levels