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Table 2 Selected pharmaceuticals derived from filamentous fungi and their applications. (Modified after [13])

From: Growing a circular economy with fungal biotechnology: a white paper

Pharmaceutical Remark
β-lactams Penicillins and cephalosporins account for more than 30% of the global antibiotics market
Cyclosporin Immunosuppressant that avoids organ rejection in transplant surgery
Drospirenone Steroid hormone used as a birth control pill and traded as Slynd; in combination with an oestrogen traded under the brand name Yasmin
Echinocandins Caspofungin, micafungin and anidulafungin used for the treatment of Candida infections
Griseofulvin Antifungal used for the treatment of skin infections
Mycophenolic acid Immunosuppressant that avoids organ rejection in transplant surgery and is traded as CellCept
Myriocin Chemical analogue thereof is used to treat multiple sclerosis; approved in 2018 as Gilenya
Psilocybin Indolalkaloid currently being tested in phase II clinical trials for the treatment of major depressive disorders and is considered by the FDA as a breakthrough therapy [16]
Statins Lovastatin, simvastatin and pravastatin are used to treat cardiovascular diseases by lowering cholesterol levels