Phytochelatin synthase is required for tolerating metal toxicity in a basidiomycete yeast and is a conserved factor involved in metal homeostasis in fungi

Table 1 Distribution of PCS homologs in the fungi

Lineage	Sub-lineage	Genome sequences examined	Present/absent?	Representative(s) in phylogeny (Figure 5 )
Chytridiomycota (P)		2	Present	Catenaria, Spizellomyces
Neocallimastigo mycota (P)		1	Present	Piromyces
Blastocladiomycota (P)		2	Present	Allomyces, Batrachochytrium
Microsporidia (P)		5	Absent
Glomeromycota (P)		1	Present	Rhizophagus
Mucoromycotina (SP)	Mucorales (O)	8	Present	Mucor, Rhizopus, Phycomyces, Lichtheimia
Mucoromycotina (SP)	Mortierellales (O)	1	Present	Mortierella
Entomophthoro mycotina (SP)		1	Absent
Zoopagomycotina (SP)		0	Unknown
Kickxellomycotina (SP)		1	Present	Coemansia
Ascomycota (P)	Taphrinomycotina (SP)	7	Present	Schizosaccharomyces, Saitoella
	Saccharomycotina (SP)	35	Absent
	Pezizomycotina (SP)	180	Present only in class Pezizomycetes; absent in all other species	Ascobolus, Tuber, Wilcoxina, Pyronema
Basidiomycota (P)	Agaricomycotina (SP)	103	Absent
	Pucciniomycotina (SP)	16	Present	Sporobolomyces, Rhodotorula, Puccinia
	Ustilaginomycotina (SP)	8	Absent
	Wallemiomycetes	2	Present	Wallemia
Unclassified	Cryptomycota	1	Present	Rozella
Unclassified	Monoblepharido mycetes	1	Present	Gonapodya

The classification system is based on [56]. P = phylum; SP = subphylum; O = order.

ISSN: 2054-3085