Fig. 2

DC-SIGN targeted liposomes, DCS12-AmB-LLs and DCS78-AmB-LLs, bound significantly more efficiently to the exopolysaccharide matrices of three highly divergent fungal pathogens than untargeted AmB-LLs. a, c, e Representative photographic images of fluorescent liposomes binding to bright field images of fungal cells are presented. a C. albicans (×10 magnification). c A. fumigatus (×10 magnification). e C. neoformans (×20 magnification). b, d, f The relative area of red fluorescent liposome binding (log₁₀) was quantified as shown in scatter bar plots on the right. N = 10 for each bar. f The scale of the plot for C. neoformans had to be expanded from three to five logs to accommodate more widely distributed data. Standard errors and P values are indicted