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Fig. 1 | Fungal Biology and Biotechnology

Fig. 1

From: Class-II dihydroorotate dehydrogenases from three phylogenetically distant fungi support anaerobic pyrimidine biosynthesis

Fig. 1

Phylogenetic tree of fungal Ura9 orthologs. An orthology search using L. kluyveri Class-II dihydroorotate dehydrogenase (LkUra9; UniProt KB accession number: Q6V3W9) as query yielded 331 fungal and 73 bacterial Ura9 orthologs (Additional file 1). These Ura9 orthologs were used to calculate a maximum-likelihood phylogenetic tree which was rooted using the bacterial clade as outgroup, and for which only bootstrap values above 75 are shown. Blue boxes indicate species capable of pyrimidine-prototrophic anaerobic growth. Numbers of sequences in collapsed clades are indicated and include Bacteria (clade 1), Basidiomycota (clade 2, 3 and 5) and Ascomycota (clade 4). The raw phylogenetic tree in phyml format is provided in Additional file 3, and interactive visualization is provided in iTOL (https://itol.embl.de/export/19319025314544511632749060)

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Fungal Biology and Biotechnology

ISSN: 2054-3085

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