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Table 2 Summary of phenotypic consequences following expression of predicted ArfA GEFs or GAP using 0 or 0.2 µg/ml Dox

From: Functional exploration of co-expression networks identifies a nexus for modulating protein and citric acid titres in Aspergillus niger submerged culture

PhenotypeMutant strain/Dox concentration
secG (0 µg/ml Dox)geaB (0.2 µg/ml Dox)ageB (0.2 µg/ml Dox)
Filamentous growth++++++
Colony development+++++++
Pellet formation during protein production++++++
Extracellular protein++++++
Pellet formation during organic acid production+++++
Extracellular citric acid+++++++++
  1. Phenotypic deviations from the progenitor are indicated as dispensable (−), moderate (+) or essential (+++). For quantification, please see Figs. 2, 3, 4, 5, 6 and 7