Fig. 5From: Functional exploration of co-expression networks identifies a nexus for modulating protein and citric acid titres in Aspergillus niger submerged cultureA. niger genes geaB and ageB, but not secG, have critical impacts on protein titres during submerged culture. Total protein in supernatant was determined using a Bradford assay, which was normalised to fungal dry weight. Pairwise Student‘s t-tests were conducted between conditional expression mutant relative to the MA70.15 control at respective Dox concentrations (μg/ml). p values are indicated as (< 0.05, *). Note that mutants TC4.5 and TC5.6 performed comparably to their isogenic comparator, and are omitted from this figure for clarityBack to article page