Fig. 5

A. niger genes geaB and ageB, but not secG, have critical impacts on protein titres during submerged culture. Total protein in supernatant was determined using a Bradford assay, which was normalised to fungal dry weight. Pairwise Student‘s t-tests were conducted between conditional expression mutant relative to the MA70.15 control at respective Dox concentrations (μg/ml). p values are indicated as (< 0.05, *). Note that mutants TC4.5 and TC5.6 performed comparably to their isogenic comparator, and are omitted from this figure for clarity