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Fig. 4 | Fungal Biology and Biotechnology

Fig. 4

From: Itaconic acid degradation in Aspergillus niger: the role of unexpected bioconversion pathways

Fig. 4

Hypothetical model of IA bioconversion in A. niger. Itaconate bioconversion presumably takes place in the mitochondrion where itaconate is converted to itaconyl-CoA by action of IctA and further hydrated to citramalyl-CoA by IchA. CclA facilitates the final conversion of citramalyl-CoA into pyruvate and acetyl-CoA. Concomitantly an parallel pathway can convert itaconate into 1-methyl itaconate

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