Translocated duplication of a targeted chromosomal segment enhances gene expression at the duplicated site and results in phenotypic changes in Aspergillus oryzae

Table 2 Percent increase in upregulated genes in the triplicated chromosomal region of the I-8 strain

COG description	Total	Up-regulated genes	%	Duplicated region	Up-regulated genes	%
[A] RNA processing and modification	176	9	5	8	7	88
[B] Chromatin structure and dynamics	38	3	8	4	3	75
[C] Energy production and conversion	371	42	11	9	5	56
[D] Cell cycle control, cell division, chromosome partitioning	101	13	13	5	5	100
[E] Amino acid transport and metabolism	453	60	13	18	14	78
[F] Nucleotide transport and metabolism	97	11	11	5	5	100
[G] Carbohydrate transport and metabolism	500	70	14	27	24	89
[H] Coenzyme transport and metabolism	133	13	10	4	3	75
[I] Lipid transport and metabolism	314	39	12	12	9	75
[J] Translation, ribosomal structure and biogenesis	277	8	3	6	6	100
[K] Transcription	180	10	6	9	8	89
[L] Replication, recombination and repair	172	14	8	7	5	71
[M] Cell wall/membrane/envelope biogenesis	98	10	10	5	3	60
[N] Cell motility	2	0	0	0	0	0
[O] Posttranslational modification, protein turnover, chaperones	390	21	5	12	10	83
[P] Inorganic ion transport and metabolism	195	18	9	9	4	44
[Q] Secondary metabolites biosynthesis, transport and catabolism	447	54	12	9	5	56
[R] General function prediction only	1370	138	10	51	24	47
[S] Function unknown	333	29	9	16	14	88
[T] Signal transduction mechanisms	310	21	7	8	3	38
[U] Intracellular trafficking, secretion, and vesicular transport	241	10	4	9	7	78
[V] Defense mechanisms	50	11	22	0	0	0
[W] Extracellular structures	3	0	0	0	0	0
[Y] Nuclear structure	6	0	0	0	0	0
[Z] Cytoskeleton	94	12	13	2	2	100
Unannotated	5659	537	9	211	118	56
Total	12,010	1153	10	446	284	64

*p < 0.02 and fold change > 1 indicate upregulated genes
% increase shows the percent ratio of upregulated genes to total genes in the whole genome or that of the genes in the duplicated region

ISSN: 2054-3085