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Table 2 Titres of beauvericin and bassianolide obtained from bioreactor cultivations

From: Aspergillus niger is a superior expression host for the production of bioactive fungal cyclodepsipeptides

Cultivation condition Maximum titre (mg/L)
Beauvericin (run 1/run 2) Bassianolide (run 1/run 2)
Standard cultivation condition 113.9/112.9 281.8/362.5
Precursor addition after 0 h 53.1/52.9 n.d.
No pH control 70.7/6.3 n.d.
  1. Titres of beauvericin and bassianolide produced in transformants DSc1.4 and SB19.23 under standard and modified cultivation conditions (for details see text). Bioreactor runs were performed in duplicates (run 1 and run 2)
  2. n.d. not done