Fig. 12

HPLC–DAD profiles of the wild type (a) and ∆PKS (b) strain, as well as the HPLC–MS profile comparison of endocrocin (c), clavorubin (d) and secalonic acid (e) between the wild type and ∆PKS strain. Strains were grown under conditions favorable for the pigment production. The relative difference between the mass spectrometric signal intensity is represented. The peaks in (a) are endocrocin (21.8 min), clavorubin (22.8 min) and two secalonic acid derivatives with a retention time of 34 and 36 min