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Table 1 Summary of BGCs of C. gorgonifer NG_p51 as predicted by antiSMASH

From: Genome analysis of Cephalotrichum gorgonifer and identification of the biosynthetic pathway for rasfonin, an inhibitor of KRAS dependent cancer

  1. Columns: ID: Cluster ID as assigned by antiSMASH; BB-gene(s): gene number of the key-enzyme encoding genes; type: type of key-enzyme; Expression: Expression of backbone genes at 24 h and 48 h are depicted as a 2-zone heatmap (weak expression | red → blue |strong expression), based on their RPKM value. An arbitrary log-value of 1 was considered as a biologically relevant expression threshold under which, the expression was set to zero. The column “Δ” depicts the differential expression between 24-h and 48-h samples and is visually supported by a 3-zone heatmap (down-regulated @ 48 h | blue → white → red | up-regulated @ 48 h) with zero being the turning point. A significance value of p < 0.05 was applied as threshold which is indicated by an Asterix near the differential expression value. If the differential expression is higher than twofold, it is indicated with an additional “+”. The Cat.: Expression Category (Cat1: Silent at 24 h and 48 h; Cat2: Expressed at either 24 h or 48 h (i.e., differentially expressed); Cat3 (Expressed at both 24 h and 48 h). Best scoring homolog BGCs in other species that were found by antiSMASH are also displayed together with their similarity in % and references